Drinking four cups of coffee a day may endanger health in under-55s, a large study on over 40,000 individuals has claimed.
Scientists have found a greater than 50% increased mortality risk in both men and women younger than 55 years of age who drank more than 28 cups of coffee a week.
The study of more than 40,000 individuals suggests that younger people in particular may need to avoid heavy coffee consumption.
A multicentre research team investigated the effect of coffee consumption on death from all causes and deaths from cardiovascular disease in the Aerobics Center Longitudinal Study (ACLS) cohort, with an average follow-up period of 16 years and a relatively large sample size of over 40,000 men and women.
Between 1979 and 1998, nearly 45,000 individuals aged between 20 and 87 years old participated and returned a medical history questionnaire assessing lifestyle habits (including coffee consumption) and personal and family medical history.
The investigators examined a total of 43,727 participants (33,900 men and 9,827 women) in their final analysis. During the 17-year median follow-up period there were 2,512 deaths (men: 87.5%; women: 12.5%), 32% of these caused by cardiovascular disease.